Wu, Pengfei; You, Tingting; Ren, Qingyuan; Xi, Hongyan; Liu, Qingqing; Qin, Fengjuan; Gu, Hongfei; Wang, Yu; Yan, Wensheng; Gao, Yukun; Chen, Wenxing; Yin, Penggang

NANO RESEARCH

2022, , 1998-0124

Wu, Pengfei; You, Tingting; Ren, Qingyuan; Xi, Hongyan; Liu, Qingqing; Qin, Fengjuan; Gu, Hongfei; Wang, Yu; Yan, Wensheng; Gao, Yukun; Chen, Wenxing; Yin, Penggang

Interface regulation plays a key role in the electrochemical performance for biosensors. By controlling the interfacial interaction, the electronic structure of active species can be adjusted effectively at micro and nano-level, which results in the optimal reaction energy barrier. Herein, we propose an interface electronic engineering scheme to design a strongly coupled 1T phase molybdenum sulfide (1T-MoS2)/MXene hybrids for constructing an efficient electrocatalytic biomimetic sensor. The local electronic and atomic structures of the 1T-MoS2/Ti3C2TX are comprehensively studied by synchrotron radiation-based X-ray photoelectron spectroscopy (XPS), as well as X-ray absorption spectroscopy (XAS) at atomic level. Experiments and theoretical calculations show that there are interfacial stresses, atomic defects and adjustable bond-length between MoS2/MXene nanosheets, which can significantly promote biomolecular adsorption and rapid electron transfer to achieve excellent electrochemical activity and reaction kinetics. The 1T-MoS2/Ti3C2TX modified electrode shows ultra high sensitivity of 1.198 mu A/mu M for dopamine detection with low limit of 0.05 mu M. We anticipate that the interface electronic engineering investigation could provide a basic idea for guiding the exploration of advanced biosensors with high sensitivity and low detection limit.