南京大学生物系本科毕业;中国科学院上海药物研究所博士毕业。2009年由中国科学院神经科学研究所加入上海光源,从事同步辐射生物医学研究和相关工程建设。作为项目负责人完成国家、省部级课题7项。 于国内率先将同步辐射影像应用于药物制剂研究,建立相关实验范式。 将同步辐射技术与我国特有生物资源相结合,开展洞穴鱼颅脑结构比较解剖和演化研究。近年来开展同步辐射的脑影像研究。
1. 基于同步辐射的脑成像及相关方法学
2. 基于三维多模态影像的比较解剖与进化
[1] 国家自然科学基金面上项目, 基于同步辐射显微CT的中国特有金线鲃属鱼类头部形态及对洞穴环境的适应演化研究,项目负责人,2017.01-2018.12
[2] 遗传资源与进化国家重点实验室开放课题,洞穴金线鲃头部三维形态及适应演化,项目负责人,2016.04-2018.03
[3] 上海市科委自然科学基金,基于同步辐射显微CT的我国特有鱼类头部结构演化研究,项目负责人,2015.01-2017.12
[4] 国家自然科学基金重点项目, 桥接细胞与整体的纳米药代动力学研究,参与,2015.01-2019.12
1. 文章:
[1] He Y*, Lundberg J, Yang J, Yang JX. A synchrotron microtomographic osteology of Chinese subterranean catfish: description and systematic analysis. Journal of Ichthyology, 2025, 65 (2):205-238.
[2] He Y*, He DK*. X-ray microtomography study of cranium, pectoral fin and girdle, and Weberian apparatus development in juvenile locah Triplophysa stewarti (Nemacheilidae). Journal of Ichthyology, 2023, 63 (2):179-191.
[3] Wen HM, Wang Y, Yang X, Yang S, Luo T, He Y*, Zhou J*. Variable eyes degeneration of the cave carp Sinocyclocheilus bicornutus (Cyprinidae) from Guizhou province, Southwest China. Journal of Ichthyology, 2023,63 (1):43-47.
[4] He Y*, Chen YX*, Yang J, Page L. Phylogenetic analyses and osteological comparison of cave spined loach Bibarba parvoculus (Cypriniformes: Cobitidae) and its surface congener. Zoological Journal of the Linnean Society, 2021.191(4):1059-1074.
[5] Lan T, Zhao YL, Zhao FC, He Y, Martinez P, Strausfeld. Leanchoiliidae reveals the ancestral organization of the stem euarthropod brain. Current Biology, 2021, 31: 1-8.
[6] 和友*, 王晓爱, 潘晓赋, 杨君兴*. 滇池金线鲃视顶盖组织学观察. 复旦学报(自然科学版),2021. 60(1): 120-125.
[7] He Y*, Berra T, Wedd D. A Microtomographic Osteology of the Forehead Hook of Nurseryfish, Kurtus gulliveri (Perciformes: Kurtidae). Copeia, 2016, 104(4):897-906.
[8] Yang JX*, …, He Y, …, et al. The Sinocyclocheilus cavefish genome provides insights into cave adaptation. BMC biology, 2016. 14(1).
[9] 和 友. 同步辐射与生命组织结构研究. 科学, 2015, 67 (6): 24-27.
[10] He Y*, Chen XY, Xiao TQ, Yang JX*. Functional morphology of the horn in cavefish Sinocyclocheilus hyalinus revealed by synchrotron X-ray microtomography. Zoological Research, 2013, 34(5):531128.
[11] Yin XZ, Li HY, Guo Z, Wu L, Chen FW, Matas M, Shao Q, Xiao TQ, York P*, He Y*,Zhang JW*. Quantification of the relative importance of swelling and erosion in the controlled release of poorly water-soluble drugs using statistical modelling and synchrotron radiation X-ray computed microtomography. The AAPS Journal, 2013, 15(4): 1025-1034.
[12] Yin XZ, Li HY, Liu RH, Chen J, Ji JQ, Chen J, Shao Q, Xiao TQ, York P*, He Y*, Zhang JW*. Fractal structure determines controlled release kinetics of monolithic osmotic pump tablets. Journal of Pharmacy and Pharmacology, 2013, 65(7):953-959.
[13] Li HY, Yin XZ, Ji JQ, Sun LX, Shao Q, York P, Xiao TQ, He Y*, Zhang JW*. Microstructural Investigation to the Controlled Release Kinetics of Monolith Osmotic ump tablets via Synchrotron Radiation X-ray Microtomography. International Journal of Pharmaceutics, 2012, 427(2):270-275.
2. 论著章节
[1] 和 友. 第四章 脑研究中的荧光蛋白探针. 《药理学进展2010》. 主编:苏定冯. 人民卫生出版社. 2011:64-75.

